Radiance System
Three prescriptions for tone and brightness: tretinoin at night, a vitamin C and copper peptide cream, and a once-weekly capsule. Each has its own evidence; they are prescribed together as one system.
SELECT A PLAN
- Guided by a licensed provider
- Three products, one shipment, one plan
- Free shipping, discreet packaging
- Cancel anytime
Renews at $705 every 5 months unless you cancel. If your provider doesn't approve your protocol, our team processes a full refund.
Product details
- Tretinoin 0.05%
- Niacinamide 5%
- Sirolimus 3mg | Zinc 5mg
- Estriol
- Copper Peptide (GHK-Cu)
- Vitamin C
Licensed Providers
503A/B Pharmacy Standard
HIPAA Compliant
No Appointment Needed
Cancel Anytime
OUR STANDARD
Medical-Grade Skincare
All of our products are made with nourishing, skin-loving ingredients that help support the integrity of your skin.
We don't hide behind vague "clean beauty" marketing. Our formulas are prescribed by licensed providers and made with clinically studied ingredients chosen to help repair, protect, and support your skin barrier. This is real medicine, designed for real results.
HOW TO USE
Radiance System
Tretinoin at night, two or three nights a week to start. The estriol cream nightly, building to daily. One capsule a week with food. Your provider sets the order and the pace.
Tretinoin Repair Cream
Copper Peptide + Estriol Cream
Sirolimus + Zinc Capsules
The Results Speak for Themselves
- 68%saw visible improvement on tretinoin within 24 weeks, versus 43% using a plain cream.¹
- 61%at least 61% shallower wrinkles and smaller pores after six months of 0.3% estriol cream, in a study of 59 women in perimenopause.²
- 2 yearsof continued improvement on tretinoin, structure intact.³
What to Expect
- Weeks 1 to 2A little dryness or flaking on tretinoin nights. Vitamin C may tingle at first.
- Weeks 3 to 6Brightness comes first, from the vitamin C cream, and skin feels smoother and more rested as the tretinoin adjustment passes.
- Weeks 8 to 12Tone evening out, fine lines softening, a clearer surface overall.
- Month 3 and onThe capsule course runs six months; the creams carry on with daily SPF. Results build with consistency.
SAFETY, PLAINLY
SAFETY, PLAINLY
Common side effects
From tretinoin: dryness, peeling and redness in the first weeks. From vitamin C: mild tingling. From the capsule: mouth ulcers are the most reported effect at low weekly doses; cholesterol and blood sugar are checked by your provider.
Sun, actives and interactions
Tretinoin and vitamin C increase sun sensitivity; daily SPF. Sirolimus is processed by CYP3A4; azole antifungals, some antibiotics, grapefruit and certain statins can change its level. Tell your provider everything you take.
Who should not use the system
Currently prescribed only for women. Not for you if you are pregnant, nursing or trying to conceive, or if you have an active infection, a weakened immune system or upcoming surgery. Each product's own exclusions apply.
When to contact your provider
Anytime through your account. Promptly for severe irritation, fever, a wound that will not heal, persistent mouth sores, or signs of infection.
How it works
What Happens After You Start
Your Assessment Goes to a Licensed Provider
A few minutes of questions about your health, history, and goals, no appointment required. The provider reviews your answers against what you've requested, and nothing is compounded or shipped until they approve.
Your Prescription Ships After Approval
Compounded for you by a licensed pharmacy, then shipped to your door with everything you need to start: your medication, supplies, and instructions for use.
Continuous Provider Care
Your prescription isn't a one-off purchase. At each check-in or renewal, your provider revisits what you're prescribed.
Who’s behind every order
Held to the Highest Standard
Prescribed by a licensed provider, fulfilled by a state-licensed 503A or 503B pharmacy, with documented ingredients, every time.
Provider
Licensed to prescribe in your state. Nothing is compounded or shipped without their approval.
Pharmacy
Compounded to your individual prescription by a 503A pharmacy, licensed and inspected by its state board of pharmacy.
Ingredients
Active ingredients with certificates of analysis for identity and purity.
COMMON QUESTIONS
COMMON QUESTIONS
RELATED
SOURCES
- J Am Acad Dermatol24-week vehicle-controlled trial of 0.05% tretinoin cream, 296 people
- Int J DermatolSix-month open-label study of 0.3% estriol cream in 59 perimenopausal women; no placebo group
- Am J Clin DermatolTwo-year placebo-controlled trial of 0.05% tretinoin cream, 204 people
Results may vary and are not guaranteed. Compounded medications are customized to meet individual patient needs and are not reviewed by the FDA for safety, efficacy, or quality.
All product imagery is for representation only and does not represent the label you may receive from our licensed pharmacy partners. Your health information and medical history will be assessed by licensed physicians, who will decide if you are eligible for treatment and determine a treatment plan and medication if appropriate.
The information anywhere on this website does not constitute medical advice and should be used for informational purposes only and does not establish a patient/doctor relationship. Please make sure to discuss the risks and benefits of any treatment with your medical provider before beginning treatment.