TWO SIGNALS
30%
In a study of 18 healthy men, blocking GIP cut the insulin released after a glucose drink by 30%, compared with 8.6% when GLP-1 was blocked. Tirzepatide acts on both hormones.1
For appetite that does not settle after eating. Tirzepatide acts at both the GIP and GLP-1 receptors, prescribed by a licensed clinician for your individual therapeutic needs and compounded by a state-licensed pharmacy.
SELECT A PLAN
Renews at $3,032 every 6 months unless you cancel. If your provider doesn't approve your protocol, our team processes a full refund.
WHAT IT IS
After you eat, your gut releases two hormones: GLP-1, which signals fullness to the brain and slows how quickly the stomach empties, and GIP, which helps your body release insulin in response to the meal. In their natural form, both are broken down within minutes. Tirzepatide is a dual agonist: a single molecule built to act on both receptors and to last, so both signals persist between meals. Semaglutide acts on GLP-1 alone; tirzepatide acts on both.
Tirzepatide is prescribed and compounded for you by a licensed pharmacy, not manufactured as a branded product. Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality.

STUDIED FOR
Tirzepatide works on two hormones your gut releases after every meal, GLP-1 and GIP. Here's what research shows about those signals, and about what losing weight does for your health.
TWO SIGNALS
30%
In a study of 18 healthy men, blocking GIP cut the insulin released after a glucose drink by 30%, compared with 8.6% when GLP-1 was blocked. Tirzepatide acts on both hormones.1
METABOLIC HEALTH
58% lower risk
In a landmark study of 3,234 adults with prediabetes, a program aiming for 7% weight loss cut the risk of developing type 2 diabetes by 58%.2
THE LONG GAME
A year or more
After weight loss, the body's hunger hormones stay elevated for at least a year, pushing appetite back up. Lasting results take more than willpower.3
SAFETY, PLAINLY
Most commonly gastrointestinal: nausea, vomiting, diarrhea, constipation and abdominal discomfort, often strongest after the first dose and after dose changes. Injection-site irritation and fatigue can also occur. Tell your provider what you are experiencing; the schedule can be adjusted.
This medication slows gastric emptying, which can affect how other oral medications are absorbed. Tell your provider about everything you take, including insulin or other diabetes medications, since dose changes may be needed.
Not for you if you are pregnant, nursing, or trying to conceive, or if you have a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2. Tell your provider about pancreatitis, gallbladder disease, or diabetic retinopathy.
Anytime through your account. Promptly for severe or persistent abdominal pain, persistent vomiting, signs of an allergic reaction, or anything that doesn't feel right.
How it works

A few minutes of questions about your health, history, and goals, no appointment required. The provider reviews your answers against what you've requested, and nothing is compounded or shipped until they approve.

Compounded for you by a licensed pharmacy, then shipped to your door with everything you need to start: your medication, supplies, and instructions for use.

Your prescription isn't a one-off purchase. At each check-in or renewal, your provider revisits what you're prescribed.
Who’s behind every order
Prescribed by a licensed provider, fulfilled by a state-licensed 503A or 503B pharmacy, with documented ingredients, every time.
Provider
Licensed to prescribe in your state. Nothing is compounded or shipped without their approval.
Pharmacy
Compounded to your individual prescription by a 503A pharmacy, licensed and inspected by its state board of pharmacy.
Ingredients
Active ingredients with certificates of analysis for identity and purity.
COMMON QUESTIONS
REFERENCES
The sources behind the findings on this page. Each one is labeled and linked to its source.
HUMAN TRIAL, N=18
Blocking GIP reduced insulin secretion after oral glucose by 30%, against 8.6% for GLP-1, in healthy men
Gasbjerg et al., 2019 (opens in a new tab)HUMAN TRIAL, N=3,234
A lifestyle program with a 7% weight-loss goal reduced the incidence of type 2 diabetes by 58% against placebo in adults with prediabetes
Knowler et al., 2002 (opens in a new tab)HUMAN STUDY, N=50
One year after diet-induced weight loss, hunger hormones had not returned to baseline and leptin remained lower
Sumithran et al., 2011 (opens in a new tab)Results may vary and are not guaranteed. Compounded medications are customized to meet individual patient needs and are not reviewed by the FDA for safety, efficacy, or quality.
All product imagery is for representation only and does not represent the label you may receive from our licensed pharmacy partners. Your health information and medical history will be assessed by licensed physicians, who will decide if you are eligible for treatment and determine a treatment plan and medication if appropriate.
The information anywhere on this website does not constitute medical advice and should be used for informational purposes only and does not establish a patient/doctor relationship. Please make sure to discuss the risks and benefits of any treatment with your medical provider before beginning treatment.